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Dropping weight can improve our resilience PDF Print E-mail
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Monday, 03 May 2010
Dropping pounds improves our resistance - results from the work of two independent teams of researchers.

Australian scientists from the Garvan Institute of Medical Research in Sydney showed that even moderate weight loss can reverse many adverse changes observed in the immune system of obese people, especially those who suffer from diabetes or type 2 Work on this subject appeared in the journal "Journal of Clinical Endocrinology Metabolism. As the authors point out, part of the immune system includes many different types of cells, whose job is to protect the body against bacteria, viruses or other pathogenic microbes, and cancer. The balance between these cells determines our health. When under the influence of various factors, which must also be an unhealthy diet and overweight, this harmony can lead to the development of various diseases - not just infectious. Previous studies have shown that excess body fat, especially around the abdomen, increases the number of immune cells that stimulate inflammation in our body. Some of them are located in adipose tissue, and part circulates in the blood and can damage other cells and tissues. Research suggests, for example, that inflammatory cells are involved in the development of coronary heart disease and other cardiovascular diseases. They are also suspected of involvement in the development of Type 2 diabetes in obese people. Scientists from Sydney carried out research in a small group of 13 obese people with type 2 diabetes or a condition called. All for 24 weeks reduced calorie diet to 1000-1600 calories per day. After the 12th week of their band was founded on the stomach, to further reduce the amount of food consumed. "It turned out that even the moderate drop in weight - about 6 kg - enough to restore the level of proinflammatory cells in the blood to that observed in lean people," - says study co-author Katherine Samaras. Generally, in lean patients, scientists have noted a decrease of 80 percent. number of proinflammatory cells described in brief as Th1 and decreased activity of other immune cells involved in inflammation, including monocytes, neutrophils and macrophages in adipose tissue. Interestingly, it also appeared that the assessment of activity of immune cells in fat may help predict the effects obtained by a person lose weight using diet and bariatric surgery. In studies, those with more active macrophages lose less weight. According to Samaras, they should remind people that excess body fat negatively affects their immune system, and hence - the chances of survival. Proof of this can also be research conducted by researchers from Tufts University in Boston (Massachusetts), who showed that reducing calorie diet can improve the efficiency of our immune system to fight infection. Article about it published a letter from the Journal of Gerontology, Biological Sciences. " Experiments were conducted in the group of 46 overweight people (but not obese), aged from 20 to 40 years of age. Some of them applied for 6 months, reduced-calorie diet with 30 percent. And some consumed by only 10 percent. fewer calories. After half a year of diet in both groups improved activity of T cells responsible for fighting many infections, although the group on a diet of 30 percent. less calorific effects were better. In our opinion, this discovery indicates that limiting calorie intake can be beneficial for us - decreased with age.

 
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